Generally, it is discovered through testing, meaning that a patient is usually already experiencing symptoms that have led him or her to see a medical professional. With so many factors that can cause a low white blood cell count, it is important to get comprehensive tests that can lead to an accurate diagnosis of the underlying cause. Side effects of chloroquine overdose Chloroquine method Plaquenil helping stomach inflammation Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Jan 27, 2014 · My rheumy has never mentioned that Plaquenil can cause a low white blood cell count, this is strange as mine has always been between 1.0 and 2.0, but mostly hovers around 1.2. ANSWER A low white blood cell count almost always is related to a decrease in a type of infection-fighting white blood cell called neutrophils. When you have a low level of neutrophils, the condition is known as neutropenia. There are many causes of neutropenia, and some medications can lead to this problem. Mostly produced by bone marrow, white blood cell count will initially rise when the body is attacked by a disease. White blood cells, also called , are the warriors of the immune system. Does plaquenil cause low white blood cell count Low White Blood Cell Count - Symptoms, Causes, Treatments., Link between low white cell count and taking Plaquenil? Does plaquenil reduce rheumatoid factor in patiences with sjogrensApo hydroxychloroquine side effectsHydroxychloroquine patient infoChloroquine rheumatoid arthritis side effectsIs it necessary to wean off of plaquenil Treatment for leukopenia depends on which type of white blood cell is low and what’s causing it. You may need other treatments to take care of any infections that develop from not having enough. Leukopenia Symptoms, Causes, and Treatment. Mayo Clinic Q and A What causes low white blood cell count?. Will you have White blood cell count increased with Plaquenil.. Infection Viruses can affect your bone marrow and cause low WBCs for a while. Severe infections, like blood infections, can lead to your body using up WBCs faster than it can make them. HIV kills a specific kind of white blood cell. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Dugan on plaquenil and low wbc This drug can effect the bone marrow and make the white blood count and platelets low. Your doctor may want to stop this medication, but don't stop it till you talk to the doctor. Good luck! Low White Blood Cell Count Symptoms. A low white blood cell count could be an indication of some underlying disease or disorder. Here is a brief overview about the symptoms and common causes of the condition.