While there is good clinical evidence demonstrating the drug’s efficacy in rheumatoid arthritis and lupus, there are very few studies looking at hydroxychloroquine as a treatment for Sjögren’s. The studies that do exist show mixed results (some show Nonetheless, despite the lack of clinical studies, rheumatologists feel that hydroxychloroquine may have a potential beneficial effect in helping patients with symptoms of fatigue and achiness, which are common complaints in patients with Sjögren’s. Should i take hydroxychloroquine if i have high liver enzymes Plaquenil scleraderma Chloroquine physical properties Plaquenil hydroxychloroquine is a Disease Modifying Anti-Rheumatic Drug DMARD that is widely used to reduce inflammation pain and swelling in the treatment of many types of arthritis and lupus. Plaquenil is also known as a treatment for malaria, a blood-borne parasite spread by mosquitoes in many tropical and sub-tropical environments. Yes, Plaquenil suppresses the immune system. Autoimmune disease such as Sjogrens occurs when the body gets "confused" and attacks healthy tissue instead of just attacking the germs. Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system. Plaquenil is a prescription medication used to reduce pain and swelling caused by diseases of the immune system such as rheumatoid arthritis, juvenile arthritis, and systemic lupus erythematosus SLE. This medication belongs to a group of drugs called DMARDs disease modifying antirheumatic drugs which work by suppressing the excessive activity of the immune system. The good news is that hydroxychloroquine targets the immune system without causing an increase in the risk of infection or cancer that can be seen with other immunosuppressant medications. How the drug works is unclear, but recent research has pointed to an inhibitory effect on toll-like receptors that are proteins involved with inflammation. Plaquenil works for what diseases Started on Plaquenil Although Blood Work was Negative., Do either hydroxychol/Plaquenil put you at risk for. Hydroxychloroquine plaquenil reviewsChloroquine in transfectionIs plaquenil harmfulHydroxychloroquine sulfate 200 mg buyPlaquenil kidney side effects Hydroxychloroquine Plaquenil, a drug designed to treat malaria, is often helpful in treating Sjogren's syndrome. Drugs that suppress the immune system, such as methotrexate Trexall, also might be prescribed. Surgery. A minor procedure to seal the tear ducts that drain tears from your eyes punctal occlusion might help relieve your dry eyes. Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic. Plaquenil - Side Effects, Uses, Dosage, Overdose.. Long-Term Side Effects of Plaquenil for Rheumatoid.. What Conditions does Plaquenil Treat? Malaria caused by the Protozoa Plasmodium Falciparum. Preventive Treatment of Vivax Malaria. malaria prevention. systemic lupus erythematosus. an autoimmune disease. Preventive Treatment of Quartan Malaria. Preventive Treatment of Ovale Malaria. Malaria. May 24, 2018 Medications can include Corticosteroids. Drugs, such as prednisone, can help prevent your immune system from attacking. Antimalarial drugs. Hydroxychloroquine Plaquenil can treat mild mixed connective tissue disease. Calcium channel blockers. This category of medications, including. Allergic and psoriasis-like rashes tend to develop within the first few weeks or months of starting Plaquenil. If Plaquenil helps a serious chronic disease such as lupus, it may be taken for years. Some of these long-term users will develop grayish-blue pigmentation on. Pigmentation associated with long-term use of Plaquenil. their shins and forearms.