It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine drug adverse effects Plaquenil erectile dysfunction Biaxin and plaquenil lyme disease Plaquenil side effects on heart I have been taking brand name Plaquenil for nearly 2 years and it has done a great job keeping my RA under control, that is until last week. The druggest didn't have any brand name Plaquenil so substituted the generic, within several days I started having flare-up symptoms - stiffness, pain, exhaustion, etc etc. PLAQUENIL hydroxychloroquine sulfate tablets is indicated for the treatment of rheumatoid arthritis, and discoid and systemic lupus erythematosus, in patients who have not responded satisfactorily to drugs with less potential for serious side effects. How to use Plaquenil. Lupus and/or rheumatoid arthritis patients will most likely take this medication by mouth, usually once or twice daily or as directed. Hydroxychloroquine generally is given to adults in doses of 200 mg or 400 mg per day. In some cases, higher doses can be used. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Ingredients in plaquenil Plaquenil Drug Information, Plaquenil Hydroxychloroquine Sulfate Chloroquine diphosphate salt malariaPlaquenil eye exam protocolPlaquenil osteoarthritis treatment PLAQUENIL tablets are white, to off-white, film coated tablets imprinted “PLAQUENIL” on one face in black ink. Each tablet contains 200 mg hydroxychloroquine sulfate equivalent to 155 mg base. Bottles of 60 tablets with child resistant closure NDC 59212-562-60. DailyMed - PLAQUENIL- hydroxychloroquine sulfate tablet. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Hydroxychloroquine - Wikipedia. Each white-to-off-white, film-coated, peanut-shaped tablet with "PLAQUENIL" in black on one side contains 200 mg of hydroxychloroquine sulfate equivalent to 155 mg of base. Nonmedicinal ingredients black ink, calcium hydrogenophosphate, carnauba wax, corn starch, magnesium stearate, opadry White YS-I-7443, and polyethylene glycol 400. Do not take Plaquenil if you have ever had an allergic reaction to hydroxychloroquine, chloroquine, or related products or any of the ingredients listed under "Product Description". Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes.