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    The comparison in terms of efficacy between Zithromax and other antibiotics such as amoxicillin is complicated by the possibility of Borrelia spirochaetes turning into a cyst form which may not respond to the antibiotic over a short course. Some patients may be given both Zithromax and hydroxychloroquine (Plaquenil), an anti-inflammatory and anti-malarial drug which is sometimes used in Lyme arthritis, rheumatoid arthritis, systemic lupus erythematosus, and Sjögren’s syndrome. Hydroxychloroquine also has an anti-spirochaete action. Flagyl (metronidazole) may also be prescribed alongside Zithromax as a medication to treat anaerobic bacteria that may co-exist with Lyme disease bacteria. There is some speculation that Borrelia spirochaetes, when presented with a hostile environment such as a lack of nutrients, or the presence of certain antibiotics, can change into a cyst form which lacks the surface markers detected on diagnostic tests such as ELISA and Western blot tests for Lyme disease. Thus, an infection may appear cured when it is in fact dormant in cystic form. When the growth conditions become more favorable an intact spirochaete may emerge from the cyst and infection symptoms may then flare up again. There is little research done into this aspect of Lyme disease making it hard for doctors to know what treatment to prescribe. Zithromax effectiveness - Grassroots Coaching Zithromax Z-Pak - Severe Side Effects, Interactions. Zithromax Effectiveness Time KelTida
     
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