They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Plaquenil antiplatelet Lupus and plaquenil problems Medicines that may cause Plaquenil interactions include digoxin, cyclosporine, and mefloquine. This eMedTV resource contains a more detailed list of drugs that may interact with Plaquenil and describes the potential effects of these interactions. They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Specifically, corticosteroids and TNF tumor necrosis factor. Methotrexate decreases the activity of your body's immune system, which increases the risk of a serious bacterial infection. Some people who take methotrexate develop an infection that requires oral antibiotics; a smaller number of people will develop an infection that requires intravenous antibiotics and hospitalization. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Taking plaquenil while having infections Medications that Weaken Your Immune System and Fungal., Medications that Weaken Your Immune System and Fungal Infections Chloroquine phosphate buy online usaPlaquenil for arthritisChloroquine phosphate uses in hindiPlaquenil eye exam frequency Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine Plaquenil Side Effects Common, Severe, Long Term -. Respiratory infections while on methotrexate" Rheumatoid.. Plaquenil - Uses, Side Effects, Interactions.. Plaquenil can damage the retina of the eye. This can lead to blindness. This problem is most common when high doses are taken for a long time. If you will be taking Plaquenil for a while, it is recommended to have a thorough eye exam before starting it and every three months while taking it. But take this advice Don’t ignore changes in vision. While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. If you are prone to recurrent UTIs, you can head them off before they take hold. Unless you're in the fortunate minority of women who have never had a urinary tract infection UTI, you know the symptoms well. You might feel a frequent urgency to urinate yet pass little urine when you go. Your urine might be cloudy, blood-tinged, and strong.