I'm not completely pain free, but it's a lot better than it was. I've been on plaquenil since mid June I have had a lot of stress in my life so I can't determine what is causing what. Not seeing any improvements with pain but I just went to 0 prednisone 3 weeks ago. said give it a few months and if I don't see any improvement I might as well go off of it. Wanted to let you know that I was on plaquenil for about three years and I told my RA doctor that my fatigue was worse. It just seems like the fatigue is worse than it has ever been, and it doesn't seem to matter if I go to bed early or take a nap during the day. Woke up and cleaned the kitchen an hour later(my kitchen is a galley kitchen 8 ft maybe.no time) Took a nap. Early on I did get those stomach cramps and diarrhea. All my pain is tolerable and he sees no deformities so he says he doesn't see RA activity. Just because the pain is tolerable doesn't make me like it any better. He did a plaquenil test and sure enough it was low. Chloroquine structure activity relationship Plaquenil uk In 1956, the U. S. Food and Drug Administration approved HCQ for symptoms of lupus and rheumatoid arthritis, particularly skin inflammation, hair loss, mouth sores, fatigue, and joint pain. Dosing Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Hydroxychloroquine is generally the first line of treatment for someone who has been diagnosed with lupus. It is used for skin and joint involvement, muscle inflammation, fever, fatigue, pleurisy, to reduce the development of renal kidney disease and chronic damage, and for its steroid-sparing properties. Jan 08, 2020 I was diagnosed with SLE in Summer 2019. My rheumatologist calls Plaquenil “Lupus life insurance.” I’ve been taking it daily since June and it is working really well. My fatigue, joint pain, swelling and other issues are essentially gone. My bloodwork continues to move toward “normal” ranges in every area and I am no longer anemic. I wake up tired in the morning, get my kids fed and off to the schoolbus, and some days that's all I can do until it's time to go pick them up and make dinner, then I collapse after the kids are put to bed. I don't know if this is just the way RA is, or if it is a side effect of the medicine. Wasn't going to eat luch because I would have to move to do it.husband bought out. Kids came home, helped with homewrok, made dinner..picked up couch(because my blanket and pillow were there) Went to bed at 9. Plaquenil lupus fatigue Plaquenil for fatigue and pain DailyStrength, Hydroxychloroquine Prescriptions - LUPUS UK Areas with chloroquine or mefloquine resistanceLong term chloroquine effectsPlaquenil and sunburnHydroxychloroquine sulfate 200 mg couponHydroxychloroquine oral ulcers Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Plaquenil? Yes or No? - Lupus - Inspire. Fighting Lupus Fatigue and Boosting Energy. The only side effects from Plaquenil that most of us notice is possibly an upset stomach for a few days.sure to take with food. Depression, anxiety, and brain fog could be Lupus symptoms -- or they could be from Remicade, I'm not familiar with it's side effects. Hydroxychloroquine can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal. Mar 17, 2019 Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.