In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Distribution of malaria and chloroquine-resistant Plaquenil reuma Medication for rheumatoid arthritis instead of plaquenil Which is what its supposed to do. I went additionally on Imuran about 8 weeks ago and have had more drastic symptom reduction, but that's because Imuran is an immune suppressants whereas plaquenil is an immune modulator/anti malarial. As a heads up plaquenil took 14 weeks for me to feel the full effects. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. After 1 1/2 yrs of my Rheumatologist after me to take the Plaquenil, I'm finally doing it. I have an eye doctors appointment this week and I'll take my first pill after the check up. I am so very scared of it. Thanks to luppylupus Thank you for explaining what the Plaquenil does and how it does it. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. What does plaquenil do for autoimmune diseases Plaquenil pros and cons - Sclero Forums MAIN - Sclero Forums, Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Dermatomyositis hydroxychloroquine rashChloroquine phosphate freshwater fishLorazepam and hydroxychloroquineDoes plaquenil cause headaches Aug 27, 2014 Cookiiez95 - I tried plaquenil for 6 months on top of methotrexate rheumatoid arthritis + other autoimmune diagnoses and saw no benefit, but don't recall having negative side effects, either. It also failed to help my mom, who was on it for years, despite its failure to help. Plaquenil - @Cookiiez95 - Autoimmune diseases - 20140827.. Fear of Plaquenil - Autoimmune Disorders - MedHelp. Plaquenil Use in Autoimmune Diseases. Asked in Autoimmune Diseases, Lupus What is the treatment for lupus ? This is a really broad question that can't be answered without taking a look at the individual who is suffering from lupus. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Yes, Plaquenil suppresses the immune system. Autoimmune disease such as Sjogrens occurs when the body gets "confused" and attacks healthy tissue instead of just attacking the germs. Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system.