To characterize structural changes of HCQ retinopathy with SD-OCT after drug cessation. Setting: Private practice and academic institution. Patient Population: Patients at New England Eye Center and Ophthalmic Consultants of Boston in Boston, MA diagnosed with HCQ retinopathy and followed after drug cessation. Low-dose hydroxychloroquine in treatment of porphyria Hydroxychloroquine black box warning Plaquenil malaria dosage The screening tests. Baseline assessment. Within one year of starting hydroxychloroquine, you may be invited to a baseline screening. appointment. The purpose of this assessment is not to detect toxicity from hydroxychloroquine, but instead to ensure there are no other problems that will make screening for toxicity difficult in the future. Macular Society Eye screening for patients taking hydroxychloroquine. Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. Main Outcome Measures: SD-OCT findings suggestive of HCQ retinopathy before parafoveal ellipsoid disruption. Retrospective clinical data review by the Boston Image Reading Center. Oct testing for plaquenil Plaquenil Toxicity - Retina Image Bank, Eye screening for patients taking hydroxychloroquine Plaquenil Hydroxychloroquine and imodiumAzulfidine for rheumatoid arthritis vs plaquenil HCQ screening for identification of early toxicity is critical to allow for cessation of the drug and potential prevention of vision loss.17 The American Academy of Ophthalmology preferred practice patterns recommend screening initially for HCQ toxicity with a complete ophthalmic exam and either HVF 10-2 perimetry or Amsler grid testing, with other testing optional and at the discretion of the provider.4,18 While HVF perimetry and Amsler grid testing may show abnormalities even before the. Spectral domain optical coherence tomography as an.. Recommendations on Screening for Chloroquine and.. Hydroxychloroquine Plaquenil Toxicity and Recommendations.. Oct 21, 2010 Duration of treatment with HCQ in these patients ranged from less than one year to 22 years, daily doses from 3.0 to 7.2 mg/kg, and cumulative doses from 146 to 2628 g. Of these patients with no SD OCT abnormalities, three complained of vision changes and eight had abnormalities on HVF 10-2 perimetry. Retinal toxicity associated with hydroxychloroquine and chloroquine risk factors, screening, and progression despite cessation of therapy. Arch Ophthalmol. 2011;129130-39. Costedoat-Chalumeau N, Ingster-Moati I, Leroux G, et al. Critical review of the new recommendations on screening for hydroxychloroquine retinopathy in French. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes.