It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Hydroxychloroquine uptodate Can you take plaquenil as needed Primaquine and chloroquine are drugs used in the treatment infections OR of congenital defects and live births. Other studies have reported that HCQ is safe to use during pregnancy but had no control group 35–40. All 4 of the studies 27–30 assessed the presence of congenital defects in babies born to women with autoimmune diseases Additional file 1, Table S2 and Figure 2a. OBJECTIVE The use of hydroxychloroquine HCQ in pregnancy remains controversial. The recent demonstration that HCQ passes across the placenta, with cord blood concentrations nearly identical to those found in maternal blood, emphasizes the need for careful evaluation of pregnancies in women receiving HCQ. Malaria is more likely to cause death in a pregnant woman. If you are pregnant, talk with your doctor about the risks of traveling to areas where malaria is common. It is not known whether hydroxychloroquine passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Hydroxychloroquine use during pregnancy Too Little of a Good Thing Hydroxychloroquine in Pregnancy, Safety of hydroxychloroquine in pregnant patients with. Plaquenil eye exam aaoHydroxychloroquine plaquenil reviews Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. Hydroxychloroquine Use During Pregnancy. Hydroxychloroquine Uses, Dosage & Side Effects -. Precautions and Warnings With Hydroxychloroquine. Hydroxychloroquine Plaquenil® is a 4-amino-quinoline antimalarial medication that is widely used to treat systemic lupus erythematosus SLE, rheumatoid arthritis, and related inflammatory and dermatological conditions. It is a hydroxylated version of chloroquine, with a similar mechanism of action. An Overview of Using Plaquenil During Pregnancy. Plaquenil ® hydroxychloroquine sulfate is a prescription anti-malarial medication that is also used to treat lupus and rheumatoid arthritis. In many cases, the benefits of using Plaquenil for malaria prevention or treatment in pregnant women outweigh the risks. Until 1995, nearly all physicians stopped hydroxychloroquine Plaquenil when a patient with lupus erythematosus LE became pregnant because there were no data on whether the drug was safe during pregnancy, said Dr. Piette of Hôpital Pitié-Salpétrière, Paris.