Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Hydroxychloroquine free Stopping plaquenil before pregnancy Medication likely administered with chloroquine Hydroxychloroquine allergic reaction Methotrexate is a type of DMARD. DMARDs are a class of medications often used in the early stages of RA. A few drugs in the DMARD class were specifically made for treating RA, but methotrexate was. Rheumatoid arthritis RA, the most common form of inflammatory arthritis, can lead to significant pain, disability, and deformity, and is a multisystem autoimmune disorder. The hallmark of this disease, erosive joint destruction, results from unchecked synovial inflammation, which can damage articular cartilage and bone, with resultant loss of. Sorry to hear that you are having a lot of pain with your RA. I have lupus which mainly affects my joints and skin. I have been taking hydroxychloroquine which is the generic of plaquenil for the past three years. My rheumy recently added Imuran instead of methotrexate. Plaquenil hydroxychloroquine takes up to 3 months to begin working. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Methotrexate and plaquenil for ra Methotrexate Injection Side Effects, Dosage, Uses, and More, Perioperative Management of Medications Used in the Treatment. Chloroquine for malaria prophylaxis dosing What Conditions Does This Treat? Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions. RA and Hydroxychloroquine How Effective is it for Rheumatoid Arthritis.. Arthritis Which would you pick and why? - Plaquenil or.. RA and Methotrexate Does Methotrexate Reduce Inflammation.. Methotrexate is one of the most effective and commonly used medications in the treatment of rheumatoid arthritis and other forms of inflammatory arthritis, and also may be used to treat lupus, inflammatory myositis, vasculitis, and some forms of childhood arthritis. It is often used in combination with other medications to treat arthritis. Methotrexate vs plaquenil side effects long term and short term The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. But the Dr suggested I try Methotrexate instead. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you.