It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil and artemesia annua together Plaquenil for angioedema Long term use of hydroxychloroquine According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Is This an Emergency? If you are experiencing serious medical symptoms, seek emergency treatment immediately. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. I've read here the Plaquenil may take 4-6 months to take effect. For those who've been through it, what was the experience of "feeling better" like? Was it one day you got up and felt much more lively? For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil time to take effect Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Plaquenil Oral Uses, Side Effects, Interactions. Hydroxychloroquine ankylosing spondylitisPlaquenil lupus medicine How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. Plaquenil - How long to take effect? - Sjogren's World. Plaquenil Overview, How to Take, Side Effects, Precautions.. Severe Interactions These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. These medications may interact and cause very harmful effects. Consult your healthcare professional e.g. doctor or pharmacist for more in formation. Take this drug at the times recommended by your doctor. If you take this drug at times other than the ones prescribed, the level of the drug in your body could increase or decrease. If it increases, you could have more side effects. If it decreases, the drug might lose its effectiveness. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness.