Im thinking a rash stays a lil & doesnt come for 10 minutes & then goes. I get facial flushing BUT when I was at the rhemy the other day, I was trying to explain to him how I get this. He said "you have it right now" But said it wasnt the ONLY show up during a FLARE because mine seems to come & go ALL the time. How to treat plaquenil toxicity Chloroquine cellular toxicity Prophylaxis of malaria chloroquine Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. The fact that you do have a butterfly rash and are responding to Plaquenil would be a better indication that you do have lupus, though most dr.s will not give a true diagnosis without one of the more specific lupus tests being positive. You could develope abnormal test results in the future or you may not. Here you can read posts from all over the web from people who wrote about Butterfly Rash and Sjogren's Syndrome, and check the relations between Butterfly Rash and Sjogren's Syndrome. I am now taking plaquenil. Anyone on this and how well does it work. butterfly rash, etc. I tested positive for ANA but not the sjogren's antibodies. I've read at least a dozen online articles to try to figure things out, and I'm even more confused after reading because some of them contradict the others! Also when im cooking, I ALWAYS get it from being in/out of the oven......... THXXXX __________________Rachel Hi Rachel, I'm no expert at all...main reason I'm replying to you is because I've wondered the same thing myself. Does plaquenil take away the butterfly rash CAN A Butterfly rash come/go in minutes?, Responding to plaquenil is it lupus? DailyStrength Bull's eye maculopathy hydroxychloroquineHydroxychloroquine lyme supplements Side effects of Plaquenil and Humira that are similar include headache or stomach pain or cramps. Side effects of Plaquenil that are different from Humira include nausea, vomiting, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or hair loss. Plaquenil vs. Humira Prescription Treatment for Rheumatoid.. Butterfly Rash and Sjogren's Syndrome - Treato. Surprising Facts About Lupus That Many People Don’t Know.. Find information about common, infrequent and rare side effects of Plaquenil Oral. How long does it take for plaquenil hydroxychloroquine to work with rashes? Answers Follow Share 2 doctors weighed in How long does it take for plaquenil hydroxychloroquine to work with rashes? 2 doctors weighed in Dr. Bruce Rothschild. Internal Medicine - Rheumatology. I had a skin rash from plaquenil hydroxychloroquine. I was put. ACLE generally causes redness over the cheeks and nose. The redness is often called a “butterfly rash.” It fades over a few weeks and does not leave scarring. The rash is usually seen in people with systemic lupus who are having a flare. It can be brought on or worsened by exposure to sunlight. People with lupus must protect themselves from the sun.