I started on it just less than 2 weeks ago, and I'm surrounded by ill people at work and already have a bit of a cold (nothing severe). it is "milder" than a lot of the other dmards in terms of side effects and activity x It is listed as having a mild immunosuppressant effect in my book on RA, but one of the reasons for the blood tests is to check that your immune system is not being suppressed too much (eg checking your white blood cell levels), so you shouldn't be completely vulnerable. Even after several years of taking lots of drugs I've not found any difference in the number of colds etc I get, and loads of people on here are teachers etc who get a lot of exposure to colds and coughs without too much problem. Chloroquine tablets Cdc chloroquine resistance Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects. Plaquenil changes the way your immune system works. In some kinds of lupus, your immune system attacks your body instead of protecting it. Plaquenil tries to quiet or slow down the immune system. Hi everyone. Just wondered if anyone can tell me whether hydroxy suppresses the immune system. And if so, to what extent. I know it's not as harsh as some of the other drugs but just wondered what people's experiences are. Polly Thank you both, I thought it shouldn't be too bad and that it's pretty mild in comparison to other drugs. Always better to be well informed and I remember the consultant saying its bit a bad time of year to start on it as I've missed all the bugs round Christmas time so thought there may be a slim chance of it being suppressed. But do look after yourself, and make sure you eat well and don't get too tired as if you have a cold already you need to pamper yourself a bit more than you would have before RA. What does plaquenil do to the immune system Does plaquenil cause shingles, does it suppress the immune., Lupus Medicines Hydroxychloroquine - Brigham and Women's. The trade name of chloroquine isAffects of stopping plaquenilChloroquine diabetes Feb 19, 2020 Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine and the immune system Hi everyone. - NRAS. Plaquenil and its affect on the immune system DailyStrength. They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Specifically, corticosteroids and TNF tumor necrosis factor. So, it's possible that the plaquenil is helping, in that your immune system is calming down and moving back toward normal. As to whether it is reallying working for you - it's kinda hard to tell; if you stop taking it and you notice a difference, it's probably been helping. Plaquenil and Immune system disorder - a study from real-world data. Summary Immune system disorder is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Enbrel, and have Pain.