Plasmodium falciparum chloroquine resistance transporter

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  1. Phoenix4x User

    Plasmodium falciparum chloroquine resistance transporter


    This score cannot be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein. This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed. This subsection of the Names and taxonomy section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry.

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    Chloroquine is used extensively in malaria endemic areas in Africa to treat the uncomplicated form of Plasmodium falciparum malaria. However, the efficiency of chloroquine has been severely impacted by the recent development of chloroquine resistant plasmodium falciparum parasites. The development of chloroquine resistance by malaria parasites is increasing at an alarming rate especially in the tropical countries where it is used extensively as an antimalarial drug 2. A simple high-throughput method to detect Plasmodium falciparum single nucleotide polymorphisms in the dihydrofolate reductase, dihydropteroate synthase, and P. falciparum cloroquine resistance transporter genes using ploymerase chain reaction and enzyme linked immunosorbent assay-based technology. Investigation of the Plasmodium falciparum Food Vacuole through Inducible Expression of the Chloroquine Resistance Transporter PfCRT

    This is known as the 'taxonomic identifier' or 'taxid'. This subsection of the Names and taxonomy section contains the taxonomic hierarchical classification lineage of the source organism. Cyclic redundancy and other checksums Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)) AF030694 Genomic DNA Translation: AAF26926.1AF233064 m RNA Translation: AAF60271.1AF233065 m RNA Translation: AAF60272.1AF233066 m RNA Translation: AAF60273.1AF233067 m RNA Translation: AAF60274.1AF233068 m RNA Translation: AAF60275.1AF495376 Genomic DNA Translation: AAO85506.1AF495377 Genomic DNA Translation: AAO85507.1AF495378 Genomic DNA Translation: AAO85508.1AY651315 m RNA Translation: AAU00067.1AF468006 m RNA Translation: AAL75580.1DQ156107 m RNA Translation: AAZ81606.1DQ156108 m RNA Translation: AAZ81607.1DQ156109 m RNA Translation: AAZ81608.1DQ533840 m RNA Translation: ABF82363.1AY254700 m RNA Translation: AAP79044.1AF030694 Genomic DNA Translation: AAF26926.1AF233064 m RNA Translation: AAF60271.1AF233065 m RNA Translation: AAF60272.1AF233066 m RNA Translation: AAF60273.1AF233067 m RNA Translation: AAF60274.1AF233068 m RNA Translation: AAF60275.1AF495376 Genomic DNA Translation: AAO85506.1AF495377 Genomic DNA Translation: AAO85507.1AF495378 Genomic DNA Translation: AAO85508.1AY651315 m RNA Translation: AAU00067.1AF468006 m RNA Translation: AAL75580.1DQ156107 m RNA Translation: AAZ81606.1DQ156108 m RNA Translation: AAZ81607.1DQ156109 m RNA Translation: AAZ81608.1DQ533840 m RNA Translation: ABF82363.1AY254700 m RNA Translation: AAP79044.1 This subsection of the 'Entry information' section provides a mnemonic identifier for a Uni Prot KB entry, but it is not a stable identifier. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'. This subsection of the Names and taxonomy section shows the unique identifier assigned by the NCBI to the source organism of the protein.

    Plasmodium falciparum chloroquine resistance transporter

    Plasmodium falciparum chloroquine resistance transporter is a., Rapid Selection of Plasmodium falciparum Chloroquine.

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  4. In addition to its utility in the diagnosis of malarial infection, PCR appeared to be a must for epidemiological surveys focused on Plasmodium falciparum with resistance to aminoquinolines, as assessed by the detection of point mutations in the P. falciparum chloroquine-resistance transporter pfcrt and P. falciparum multidrug-resistance.

    • Plasmodium falciparum Chloroquine-Resistance Transporter..
    • Investigation of the Plasmodium falciparum Food Vacuole..
    • In silico modeling of Plasmodium falciparum chloroquine..

    We obtained 78 human blood samples from areas in Haiti with high transmission of malaria and found no drug resistance–associated mutations in Plasmodium falciparum chloroquine resistance transporter and Kelch 13 genes. We recommend maintaining chloroquine as the first-line drug for malaria in Haiti. Cooper RA, Lane KD, Deng B, Mu J, Patel JJ, et al. 2007 Mutations in transmembrane domains 1, 4 and 9 of the Plasmodium falciparum chloroquine resistance transporter alter susceptibility to chloroquine, quinine and quinidine. Mol Microbiol 63 270–282. View Article Google Scholar 18. Resistance to chloroquine is a public health problem worldwide. Polymorphisms of the Plasmodium falciparum chloroquine resistance transporter pfcrt and P. falciparum multidrug resistance 1 pfmdr1 genes have been linked to chloroquine resistance. Although the K76T mutation in the pfcrt gene has been shown to be a key determinant in chloroquine resistance, evidence suggests that the pfmdr1.

     
  5. vikonto Moderator

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  6. Janis Well-Known Member

    Pill with imprint PLAQUENIL is White, Figure eight-shape and has been identified as Hydroxychloroquine Sulfate 200 mg. Hydroxychloroquine is used in the treatment of lyme disease, arthritis; dermatomyositis; malaria; malaria prevention; rheumatoid arthritis and belongs to the drug classes antimalarial quinolines, antirheumatics. Plaquenil Hydroxychloroquine Side effects, Images, Uses. Multimodal Imaging in Plaquenil Toxicity Hydroxychloroquine Oral Route Description and Brand Names.
     
  7. MadTomas Well-Known Member

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