I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Is hydroxychloroquine safe while pregnant Low body fat and increase risk for chloroquine toxicity Like I have pressure on the top of my head. I nver had this before. Could this be a side effect of the Plaquenil and does it normaly go away after I take it for a while? Answer. That is an unusual side effect for Plaquenil. I would try stopping and restarting it to make sure Plaquenil is at fault. May 07, 2012 Plaquenil is used in the treatment of sarcoidosis but its main use is in the treatment of malaria. One of the side effects of taking the drug is that it affects eye sight, and eye tests, especially field of vision tests need to be done every six months. What are the side effects of Plaquenil? The most common side effects are diarrhea, nausea, vomiting, headache, dizziness, skin rash or black spots when you look at things. Most side effects will go away when your body gets used to the medicine. Tell your doctor if you have these side effects. A lower dose may stop them. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Side effects after stopping plaquenil Common Plaquenil side effects a study from FDA data - eHealthMe, Plaquenil Withdrawal – Life As An Anomaly Can i take plaquenil and prednisone at the same timePlaquenil is it good for goutWeight gain with plaquenilPlaquenil long term use If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you. Hydroxychloroquine MedlinePlus Drug Information. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. The Risk of Retinal Toxicity with Plaquenil. Feb 19, 2020 Common side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or. I was prescribed plaquenil for Sjogrens about 5 years ago by my rheumatogist. I too was afraid of the side effects and didn't realize that the disease would worsen, so I just didn't take the plaquenil. Two years later I began having pericarditis attacks and wound up in the hospital.