I am very underweight and do have chronic diarrhea, but gosh, this seems invasive as a first step in trying to figure out . Has anyone had chronic diarrhea/weight loss from Plaquenil? Plaquenil and low blood pressure Is plaquenil safe to use Diarrhea is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months, also take medication Enbrel, and have Pain. This study is created by eHealthMe based on reports of 57,706 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Ginny, I had some very minor diarrhea, nausea, cramping for about a week when I started Plaquenil. Everyone is different, but for me, taking the med about 15 min. after eating, rather than before or with a meal, makes things much easier on my stomach, even for just Advil. My rheumatologist nor the GI doctor have suggested alternate treatments to see if it could be the problem. I know it can be a temporary side effect for some, but I've been on it for a year. Plaquenil nausea diarrhea Plaquenil, stomach pain and diarrhea - Sjogren's World, Plaquenil Oral Uses, Side Effects, Interactions. How does chloroquine prevent malariaPlaquenil and rapid heartbeatApple cider vinegar interaction with hydroxychloroquinePlaquenil kopenCan plaquenil be used to treat fibromyalgia Rarely it can cause an upset stomach or diarrhea. Skin rash – Plaquenil can rarely cause a rash. Patients who experience this rare side effect should stop taking this medicine and contact their doctor. Headaches – Plaquenil can rarely cause a headache. Sun Sensitivity – Plaquenil can sometimes make the skin more sensitive to the sun. Plaquenil – RheumInfo. Plaquenil = explosive diarrhea -. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. I suspect plaquenil for giving me some episodic diarrhea. I am 100 mg dose and take it with my supper. Did they happen to anyone else and did it eventually stop with the diarrhea side effect? It helps so much with the fatigue and pain. I have a sensitive stomach and perhaps I shouldn't have eaten that salad for lunch yesterday. Apr 21, 2017 I had severe nausea and diarrhea when started on Plaquenil 2 X 200mg tabs once daily almost 3yrs ago. As I also have Crohn's Disease and an Ileostomy this was putting me at serious risk. I was told to stop the Plaquenil until my GI symptoms disappeared. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness.