After a thorough physical exam, your doctor may suggest blood tests to check for elevated levels of certain antibodies produced by the immune system. He or she may also remove a small sample of your affected skin so that it can be examined in the laboratory. Imuran and plaquenil t Plaquenil for infertility The Scleroderma Foundation Medical & Scientific Advisory Board Leadership Committee* Updated March 15, 2020. Note The following information and recommendations may change as more is learned about COVID-19. Please check back for regular updates. Anti-malarial drugs, such as Plaquenil hydroxychloroquine, is often used to manage lupus and can also be effective in scleroderma. Plaquenil is thought to interfere with communication between immune cells, which can suppress the damaging effect of an overly active immune response without raising a patient’s risk of susceptibility to infections. I may be wrong I often am! but I think there are more listed side effects for aspirin than there are for plaquenil; and by a very long shot, it would seem to be safer than steroids, especially for scleroderma patients. Basically, plaquenil's effect is to modulate the immune system, which is something that could be quite beneficial for some of us. In some cases, the skin problems associated with scleroderma fade away on their own in two to five years. Your doctor may also suggest other blood tests and imaging or organ-function tests to help determine whether your digestive system, heart or lungs are affected. Plaquenil for scleroderma Anti-Malarial Medications - Scleroderma News, Lupus and Scleroderma - Scleroderma News Chloroquine off target effectsPlaquenil and eye examsLichen planus hydroxychloroquineDifference between methotrexate and plaquenilPlaquenil side effect on eyes Does plaquenil hydroxychloroquine prevent/slow down organs from being attacked, or just mask lupus symptoms? I have a positive ANA 0 homogenous nuclear staining. Does this mean scleroderma or lupus? I also have a very slightly elevated angiotensin conv en; Does low c3c and 4 go with lupus rather than scleroderma? How does plaquinil slow the process of scleroderma and. - HealthTap. Plaquenil pros and cons - Sclero Forums MAIN - Sclero Forums. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Scleroderma is considered a rare disease with an estimated prevalence in the United States of 276–300 cases per million 1–3 and an incidence of about 20 cases per million per year 2. Females are more commonly affected 4.6 to 1 2 and it tends to be more severe among African and Native Americans than Caucasians 4,5. Nonsterodial anti-inflammatory drugs and hydroxychloroquine Plaquenil help both conditions. Most patients with pure schleroderma do not benefit from corticosteroids. Methotrexate, azathioprine, prednisone or cyclophosphamide help lupus and overlap syndromes, and perhaps scleroderma lung disease. Diagnosis. Because scleroderma can take so many forms and affect so many different areas of the body, it can be difficult to diagnose. After a thorough physical exam, your doctor may suggest blood tests to check for elevated levels of certain antibodies produced by the immune system.