Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Heme chloroquine complex Ibuprofin and plaquenil How soon does plaquenil start working For people with arthritis and hearing loss, your rheumatologist may consider starting or intensifying the use of disease-modifying antirheumatic drugs, supplementing these with steroids either oral or injected into the middle ear, and eliminating drugs such as hydroxychloroquine and chloroquine, which may damage hearing. However, like most powerful drugs, it is not without its side effects. What is being blamed on Plaquenil could be long term aspirin therapy. Or the combination of several drugs over years of therapy. Once I clear up a few other problems that are screaming louder for the moment. In the meantime, Lin says, if you have hearing loss, it makes sense to get it treated as well as it possibly can be. There's lots of room for improvement — fewer than 15 to 20 percent of those with a clinically significant hearing loss even use hearing aids. Katherine Griffin is a writer and editor in the San Francisco Bay Area. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Hydroxychloroquine and hearing loss Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil, anyone taking this, and ha. - Hughes Syndrome What happens if you stop taking your plaquenilHydroxychloroquine sulfate pregnancyChloroquine nursing responsibilitiesHydroxychloroquine ears Hearing Disorders. In 2005, Lareb, the Netherlands Pharmacovigilance Centre, reported that it received three reports of permanent hearing loss and tinnitus after long-term Plaquenil use. The article mentioned that hydroxychloroquine is chemically related to other drugs that have known toxic effects on hearing 2. Other Side Effects Long-Term Side Effects of Plaquenil for Rheumatoid.. Hearing Loss Linked to Memory Loss, Dementia - AARP. Hydroxychloroquine Plaquenil Success, Reviews and Side Effects. Hydroxychloroquine and hearing loss Introduction Hydroxychloroquine Plaquenil® is an antimalarial agent which is approved for rheumatoid arthritis, systemic lupus erythematosis, discoid lupus erythematosis, prophylaxis and treatment of acute malaria, and photodermatosis 1. In the Netherlands it has been approved since 1966. Irreversible hearing loss was developed following long-term therapy with hydroxychloroquine. The present case was a HIV-positive man who developed hearing loss following short course one month hydroxychloroquine therapy and his problem was resolved following discontinuation of hydroxychloroquine and continuation of prednisolone. Hydroxychloroquine-induced hearing loss may reversibly occur following short term therapy in HIV patients.