It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Chloroquine phosphate structure When was chloroquine invented It works against the asexual form of malaria inside the red blood cell. Chloroquine was discovered in 1934 by Hans Andersag. It is available as a generic medication. The wholesale cost in the developing world is about US$ 0.04. Nov 09, 2018 To make sure hydroxychloroquine is safe for you, tell your doctor if you have a history of vision changes or damage to your retina caused by an anti-malaria medication; heart disease, heart rhythm disorder such as long QT syndrome; diabetes; a stomach disorder; an allergy to quinine; liver. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. History of hydroxychloroquine Hydroxychloroquine sulfate C18H28ClN3O5S - PubChem, Hydroxychloroquine - Side Effects, Dosage, Interactions. Return of chloroquine antimalarial efficacy in malawiHydroxychloroquine sulfate pharmacological classPlaquenil infection Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Hydroxychloroquine Plaquenil Toxicity and.. What Is the Difference between Hydroxychloroquine and.. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis or juvenile idiopathic arthritis and other autoimmune diseases. In 1941, discoid lupus patients were treated successfully with Atabrine, a compound developed in Germany in the 1920s. In the mid-1940s, both hydroxychloroquine HCQ and chloroquine CQ had been synthesized. In 1955 HCQ was shown to be effective for both systemic lupus and rheumatoid arthritis. May 02, 2018 A study of about 200 patients with a history of hydroxychloroquine retinopathy, including 36 Asian patients, found that the pericentral pattern occurred in half the Asian patients but only 2% of the white patients. 31 The mechanism for this finding is unclear, but because pericentral retinopathy spares the macula, it can be missed using standard screening methods.