Viagra (sildenafil) is an oral drug that is used for treating impotence (or erectile disfunction, ED, the inability to attain or maintain a penile erection). It is in a class of drugs called phosphodiesterase inhibitors (PDE-5 inhibitors) that also includes It has been estimated that impotence affects 140 million men worldwide. Over half of all men with impotence are thought to have some physical (medical) cause. The remainder are believed to have psychogenic causes of impotence. Medical causes of impotence include diabetes and circulatory, neurological, or urological conditions. Penile erection is caused by the engorgement of the penis with blood. This engorgement occurs when the blood vessels delivering blood to the penis increase the delivery of blood and the blood vessels carrying blood away from the penis decrease the removal of blood. Viagra is the brand name for a medicine known as Sildenafil which has been proven to be effective for the treatment of erectile dysfunction. Sildenafil is the active ingredient and has also been available since 2013 as a generic drug. A generic drug contains the same active ingredient as a branded drug and is medically equivalent but can be produced by any generic manufacturer. Viagra was one of the first treatments to be approved for the treatment of erectile dysfunction and has been used by men across the world for over a decade with excellent results. Pfizer was the original manufacturer for Viagra and developed a patent on the product in 1996. Originally Viagra was used for the treatment of heart disease, but during clinical trials it was noticed that it also helped treat erectile dysfunction. In 1998, Pfizer received FDA approval to license the product for the treatment of erectile dysfunction.
These highlights do not include all the information needed to use VIAGRA safely and effectively. VIAGRA® (sildenafil citrate) tablets, for oral use Initial U. Approval: 1998For most patients, the recommended dose is 50 mg taken, as needed, approximately 1 hour before sexual activity. However, VIAGRA may be taken anywhere from 30 minutes to 4 hours before sexual activity. The maximum recommended dosing frequency is once per day. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. VIAGRA was shown to potentiate the hypotensive effects of nitrates and its administration in patients who use nitric oxide donors such as organic nitrates or organic nitrites in any form is therefore contraindicated [The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25 mg within a 48 hour period because concomitant administration increased the blood levels of sildenafil by 11-fold [Consider a starting dose of 25 mg in patients treated with strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, or saquinavir) or erythromycin. Clinical data have shown that co-administration with saquinavir or erythromycin increased plasma levels of sildenafil by about 3 fold [VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil. Tablets are debossed with PFIZER on one side and VGR25, VGR50 or VGR100 on the other to indicate the dosage strengths.], VIAGRA was shown to potentiate the hypotensive effects of nitrates, and its administration to patients who are using nitric oxide donors such as organic nitrates or organic nitrites in any form either regularly and/or intermittently is therefore contraindicated. PRILIGY, aadakilerin hepsinin bulunduu 18 ile 64 ya aras erkeklerdeki prematr ejaklasyonun (PE) tedavisinde endikedir. Minimal cinsel uyar ile penetrasyon ncesinde, penetrasyon annda ya da penetrasyondan ksa bir sre sonra olan ve hastann arzulad sreden nce gerekleen persistan veya rekrren ejaklasyon; ve PEnin bir sonucu olarak belirgin kiisel sknt (stres) ya da kiiler aras ilikilerde zorluk; ve Erikin erkekler (18-64 ya)nerilen doz 30 mgdr ve gerektiinde ilikiden yaklak 1 ile 3 saat ncesinde alnr. 30 mg ile etki yetersizse ve yan etkiler kabul edilebilir dzeydeyse, doz maksimum nerilen doz olan 60 mga ykseltilebilir. Uygulama skl ve sresi:nerilen maksimum uygulama skl gnde bir kezdir. Tabletlerin, tam olarak dolu en az bir bardak suyla alnmas nerilir. Prematr ejaklasyon tedavisi iin PRILIGYi seen hekim, hastadaki risk-yarar dengesini ve tedavinin daha sonraki seyrini belirlemek amacyla tedavinin ilk drt haftasnda veya 6 doz sonrasnda hasta tarafndan bildirilen yararlar ve riskleri deerlendirmelidir. PRILIGY yemeklerle birlikte ya da yemek harici alnabilir (bkz. Blm 5.2)poplasyonlara ilikin ek bilgiler: Bbrek yetmezlii: Hafif ya da orta derecede bbrek yetmezlii olan hastalarda doz ayarlamasna gerek yoktur ancak dikkatli olunmas nerilir. Ar bbrek yetmezlii olan hastalarda PRILIGY kullanm nerilmez (bkz. Karacier yetmezlii: Hafif ya da orta derecede karacier yetmezlii olan hastalarda doz ayarlamasna gerek yoktur; ancak orta derecede karacier yetmezlii olan hastalarda dikkatli olunmas nerilir.
Sildenafil citrate is a white to off-white crystalline powder with a solubility of 3.5 mg/mL in water and a molecular weight of 666.7. Viagra is formulated as blue. What preparations of sildenafil are available? Sildenafil Viagra is a blue, film-coated, rounded, diamond-shaped tablet that comes in 25, 50, and 100 mg tablets for treating impotence.